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Fighting global disease threats

The various  influenza viruses in humans. Solid squares show the appearance of a new strain, causing recurring influenza pandemics. Broken lines indicate uncertain strain identifications.

The various  influenza viruses in humans. Solid squares show the appearance of a new strain, causing recurring influenza pandemics. Broken lines indicate uncertain strain identifications.

To members and friends of the Providence Committee on Foreign Relations (thepcfr.org; pcfremail@gmail.com):

The next PCFR dinner meeting comes on Wednesday, April 19, with Dr. Rand Stoneburner,  M.D., the distinguished international epidemiologist. Dr. Stoneburner, who has done extensive work with the World Health Organization, among other public health organizations,  will talk about Zika, Ebola and the biggest threat – a global influenza pandemic. He’ll have some graphics.

 

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Commentary Robert Whitcomb Commentary Robert Whitcomb

John O. Harney: New England vs. demographics

  BOSTON

“The Great Recession and not-so-great recovery applies to all of us.”

That was University of Southern Maine professor Charlie Colgan’s  remark at at the New England Economic Partnership (NEEP) conference Oct. 13 as he noted that Maine was just two-thirds of the way back to pre-recession employment levels.

The  New England forecasts at the Fall Economic Outlook conference were  generally cautiously optimistic, sprinkled with the expressed and implied NEEP mantra: “Having said that, I could be wrong.”

It may be the dismal science, but it’s an experiment you're part of every time you go to work or buy anything.

“What is relatively unique in New England is the region’s demographics—with a rapidly aging population and steep declines in young adult population threatening the region’s workforce skills and education advantage,” said New England Forecast Manager Ross Gittell, chancellor of the Community College System of New Hampshire.

In Maine, for example, Baby Boomers and their children simply had fewer babies, so all of Maine’s added population in the next 40 years will come from in-migration, but the big sources of that in-migration—Vermont and New Hampshire—are also shrinking, said Colgan. Will productivity increase enough to keep Maine and New England competitive?

Gittell and others joked that given the demography, the region should have focused on under-18 housing instead of over-65 housing.

Colgan noted that ship and boatbuilding have returned to Maine as a major industry (thanks to more destroyers  being built at Bath Iron Works) and natural-resource industries have returned, in a sense, with Lincoln Logs coming back to Maine from China.

Colgan, by the way, is one of the professors let go recently by the University of Southern Maine—part of a higher-education disinvestment story that may say more about the future of the New England economy than any other layoff tracked by NEEP.

He warned that people in Maine see the loss of old-economy jobs such as the impending closure of the Verso paper mill in Bucksport as a tragedy, while they view the laying off of intellectuals at USM, who may be “from away” (though Colgan’s not) as a win for taxpayers.

Among tidbits from the other NEEP forecast managers:

Fairfield University professor emeritus Edward Deak noted that just 60 percent of Connecticut jobs lost during the recession have been regained in the Land of Steady Habits. No one knows whether they are as good as the jobs they’re replacing. What is clear in Connecticut, said Deak, is that “the well-to-do are doing very well.”

Connecticut has the sixth-oldest population in the U.S., though many people over age 65 are leaving the state after retiring. In retail, more purchases are being made via the Internet by working women with young children; fewer at the malls, Deak said, adding that when you look at Connecticut skylines, you don’t see any cranes. It’s all work on old buildings.

Bryant University assistant professor Edinaldo Tebaldi seemed relieved that Rhode Island is no longer first in unemployment; now it’s third. But this “gain” is associated with shrinking of the labor force, and the number of jobs is still below pre-recession levels.

New Hampshire has gone the other direction. Center for Public Policy Studies economist Dennis Delay said New Hampshire had been outperforming New England and U.S. job growth especially in early '80s, but is no longer the superstar. He showed 2012 migrants by higher educational attainments: lots of graduate or professional degrees among the foreign-born, but also many without a high school diploma. Delay noted that New Hampshire ranks high in indicators of home ownership, voter turnout and low welfare costs, but also high in student debt and low in growth of people ages 25-44—so-called wealth-building years.

 

Vermont economist Jeff Carr noted that about 90 percent of jobs  there lost during the recession had been recovered—second in New England to Massachusetts, which has fully recovered jobs. Vermont is difficult to analyze because the job totals in each sector are small. But that small size adds to anxiety about the loss of a few-hundred highly paid jobs at the closing Vermont Yankee nuke; as well as perpetual concern about IBM because its decisions are made in Armonk, N.Y. Carr also cited the importance of Vermont’s food industry, including craft brewers. (The  same day, the Vermont Foodbank reported that one-quarter of Vermont's citizens don't know where their next meal is coming from.)

Carr joked that he is in favor of financial-services bonuses in New York City and Boston because they boost Vermont's sizable second-home economy.

According to the New England regional forecast, prepared by Gittell, the regional economy will continue to see growth rates below the national average. The NEEP forecast is that total employment growth will average 1.3 percent a  year—and all the New England states are projected to have employment growth below the national average over the forecast period out to 2018.

Mark Zandi, chief economist at Moody’s Analytics, opened the conference with a presentation on the U.S. Economic Outlook. In a year or so, growth in gross regional product could go from 3% to 4 percent fueled partly by more housing, including pent-up demand among millennials who have been renting. The economist, and increasingly visible TV pundit, contended that financial aspects of economy are in great shape, especially high-income households. Middle-incomes households are still encumbered by debt, he said, but the high end does most of the spending, “though I’m not arguing economy can flourish without everyone participating,” said Zandi.

Phew. He told of his son majoring in philosophy. (Reminded me of the founder of one of the nation’s leading career-oriented online providers confiding that his child was majoring in sociology on a traditional campus.)

Despite Zandi’s general optimism, the risks include interest rates and a mélange of global issues, Zandi noted, adding that even Ebola could undermine traveling and spending (may not be rational to be so concerned about it, but people are). In response to a question, Zandi said he doesn’t think income and wealth inequality is a big issue in a given year, compared with the lack of labor. No one’s going to be writing a book about income inequality soon, he said. Really?

In his keynote address, former Maine Gov. John E. Baldacci, now at the law firm of Pierce Atwood, cited the importance of energy and exports in the region’s economic future. He hailed natural gas as the foundation fuel, while the region works toward renewables, including solar, tidal and wood.

He tied exports to tourism, noting that the owner of New Balance sneakers was introduced to Maine via ski vacations, where he was treated well, then announced plans to open plants in the state.

In a concluding panel, William Guenther, chair and CEO of Mass Insight, boasted: “Massachusetts has benefited for years from the talent cluster that we have offered business.” He noted, however, that technology-focused jobs are growing in such areas as big data analytics, cybersecurity, and computer sciences, but the state is not producing enough college graduates with degrees in science, technology, engineering or math (STEM) to keep up with demand from business. "Jobs will always come to where the talent is,” said Guenther.

Jobs also go where there’s energy work. The state and Canadian province with the most explosive job sectors are oil- and gas-rich North Dakota and Alberta.

John O. Harney is executive editor of The New England Journal of Higher Education, the online publication of the New  England Board of Higher Education (nebhe.org), where this column originated.

 

 

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Ebola isn't over in Nigeria

I was amused to read the assertions, apparently believed by many in the press, that Nigeria had conquered Ebola. Baloney. Nigeria has about 160 million people and is  among the most corrupt places on Earth. It also has porous borders and a thin public-health system.

Ebola will turn up there again.

 

-- Robert Whitcomb

 

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Commentary Robert Whitcomb Commentary Robert Whitcomb

Llewellyn King: U.S. funds for medical research falling dangerously

Two seemingly unrelated items of medical news: Ebola is devastating West Africa, and may spread around the world, and the entertaining ice bucket challenge has raised $115 million for ALS research.  

The linkage is that both diseases have needed and still need medical research. So do hundreds of other diseases and conditions.

 

The truth is that the amount of money the United States spends on medical research is falling precipitously. It has been hit by budget worries in Congress, sequestration and the decline in research funding by corporations.

 

Leo Chalupa, vice president for research at The George Washington University, said on our TV show,  ''White House Chronicle,'' last weekend that the National Institutes of Health budget for research grants has decreased by 20 percent since 2004. He said that five out of six research applications are now rejected by the NIH, the principal conduit for federal funding of biomedical research.

 

The George Washington University is a member of the Science Coalition, a group of more than 60 of the nation's leading public and private research universities. Since its establishment in 1994, the coalition has advocated for sustained federal investment in basic scientific research as a means to stimulate the economy, spur innovation and drive America's global competitiveness.”

 

The late David Fishlock, science editor of the Financial Times, wrote and spoke elegantly about the problem democracies have in sustaining scientific funding; how they tend to be heavy on the gas, and then heavy on the brakes.

 

The government funds research through its own network of institutes and laboratories, and through grants to universities and corporations. When it comes to capturing the energy and flair of young researchers, the universities are vital.

 

Jennifer Reed, associate professor in the Department of Chemical and Biological Engineering at University of Wisconsin-Madison, said on ''White House Chronicle'' that universities contract with graduate students for five years, but the federal grants for research, when they get them, can be for less time. Reed said this is devastating to the research and the lives of the young researchers. Her funding comes from the Department of Energy and is aimed at using renewable materials to make alternatives to fossil-based plastics; also energy storage.

 

The problem is acute in medical research, most of which has its genesis in grants made by the NIH. Contrary to popular belief that medical funding is shouldered in the private sector, Chalupa said pharmaceutical companies often have narrow interests in particular drugs for particular conditions. “They have shareholders to answer to,” he said.

 

But it is not just funding that bedevils research, it is politics as well. Good projects are canceled and bad ones are incubated, depending on their appeal to particular constituencies. For example, fusion research has been lavished with money compared to other nuclear research needs, including the increased use of nuclear medicine to save lives and suffering

 

Also the government funds research through many agencies, and this often reflects local or political pressure. Some researchers have found that they have to shop for funding, from NIH to the Pentagon to the National Science Foundation. Others have turned to crowd-funding, including the famed virus hunter Dr. W. Ian Lipkin, who directs the Center for Infection and Immunity at Columbia University's Mailman School of Public Health. Dr. Lipkin is now in high demand because of the Ebola crisis. But if there had been more work on viruses since the discovery of Ebola in 1976, there might now be a vaccine or other therapy to deal with the epidemic.

 

The United States is still the creative engine of the world. But without steady expenditure, it won't be firing on all cylinders. Chalupa and Reed warned that China is increasing its funding for research rapidly, and is set to overtake the United States.

 

One (or more) patient launched the iced water caper that has been so successful out of frustration with the ALS research effort. It has been creative, but it will not keep the United States as the preeminent home of brave discoveries. Or to help the sick.

 

Llewellyn King (lking@kingpublishing.com)  is host and executive producer of "White House Chronicle,'' on PBS.

 

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